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IL-2, IL-5, TNF-α and IFN-γ mRNA expression in epidermal keratinocytes of systemic lupus erythematosus skin lesions

OBJECTIVE: To analyze cytokine gene expression in keratinocytes from patients with systemic lupus erythematosus (SLE). INTRODUCTION: Keratinocytes represent 95% of epidermal cells and can secrete several cytokines. METHODS: Keratinocytes were obtained by laser microdissection from 21 patients with S...

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Principais autores: José Ronaldo M Carneiro, Hellen T Fuzii, Cristiane Kayser, Fernando L Alberto, Fernando A Soares, Emília I Sato, Luís Eduardo C Andrade
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier España 2011-01-01
Serier:Clinics
Fag:
Cytokines
Gene expression
Interleukins
Lupus
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322011000100014&lng=en&tlng=en
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