Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells

<p>Abstract</p> <p>Background</p> <p>DNA methylation, histone modifications and nucleosome occupancy act in concert for regulation of gene expression patterns in mammalian cells. Recently, G9a, a H3K9 methyltransferase, has been shown to play a role in establishment of DNA methylation at embryonic g...

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Detalhes bibliográficos

Principais autores:	Sharma Shikhar, Gerke Daniel S, Han Han F, Jeong Shinwu, Stallcup Michael R, Jones Peter A, Liang Gangning
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2012-01-01
Colecção:	Epigenetics & Chromatin
Assuntos:	G9a DNMT3A DNMT3B DNA methylation Nucleosome Maintenance Epigenetics
Acesso em linha:	http://www.epigeneticsandchromatin.com/content/5/1/3
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