Housing RCS rats under specific pathogen-free conditions mildly ameliorates retinal degeneration and alters intestine microbiota

Abstract Retinitis pigmentosa (RP) is a genetic blinding disease with over 80 causative genes. Disease progression varies between patients with similar genetic backgrounds. We assessed the association between environment, gut microbiota, and retinal degeneration in the RP rat model Royal College of...

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Autori principali:	Hadas Ketter-Katz, Rawan Saeed, Ifat Sher, Gali Altmann, Tal Shadi, Shada Dallasheh, Yael Lustig-Barzelay, Amit Sabo, George Jejelava, Rotem Hadar, Gilat Efroni, Amnon Amir, Tzipi Braun, Yael Haberman, Ygal Rotenstreich
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2024-09-01
Serie:	Scientific Reports
Soggetti:	Retinitis pigmentosa Microbiome RCS rats Retinal degeneration Photoreceptors
Accesso online:	https://doi.org/10.1038/s41598-024-70960-z
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