Use of an In Vitro Skin Parallel Artificial Membrane Assay (Skin-PAMPA) as a Screening Tool to Compare Transdermal Permeability of Model Compound 4-Phenylethyl-Resorcinol Dissolved in Different Solvents

Absorption through the skin of topically applied chemicals is relevant for both formulation development and safety assessment, especially in the early stages of development. However, the supply of human skin is limited, and the traditional in vitro methods are of low throughput. As an alternative, a...

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Hlavní autoři:	Bálint Sinkó, Vivien Bárdos, Dániel Vesztergombi, Szabina Kádár, Petra Malcsiner, Anne Moustie, Chantal Jouy, Krisztina Takács-Novák, Sebastien Grégoire
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2021-10-01
Edice:	Pharmaceutics
Témata:	Skin-PAMPA formulation skin barrier permeability pig skin safety testing
On-line přístup:	https://www.mdpi.com/1999-4923/13/11/1758
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