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SARS-CoV-2 spike protein increases angiotensin converting enzyme-2 expression and promotes an increase in glucose uptake in endothelial cells

Coronavirus Disease 2019 (COVID-19) pandemic led to 7 million deaths and more than 770 million confirmed cases worldwide. The Spike glycoprotein (SP) is responsible for recognizing and binding to angiotensin converting enzyme-2 (ACE-2) in the host cell membrane and seems to modulate host cellular si...

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Principais autores: Mariana F. Campos, Larissa E. C. Constant, Douglas E. Teixeira, Rodrigo P. Silva-Aguiar, Patrícia R. M. Rocco, Ronaldo Mohana-Borges, Gilda G. Leitão, Celso Caruso-Neves, Suzana G. Leitão, Diego Allonso
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-03-01
Serier:Acta Virologica
Fag:
COVID-19
SARS-CoV-2
spike protein, endothelial cells
HUVEC-C cells
metabolic reprogramming
Online adgang:https://www.frontierspartnerships.org/articles/10.3389/av.2024.12136/full
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