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Piperacillin/tazobactam treatment in children: evidence of subtherapeutic concentrations

ObjectivePiperacillin/tazobactam (PIP/TAZ) is used for the treatment of lower respiratory tract bacterial infections in children. This study was performed to evaluate if the current dosing regimen results in therapeutic drug concentrations.Patients and methodsPatients suspected or proven to have low...

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Principais autores: Panpan Ye, Jinyi Shi, Zixuan Guo, Xinmei Yang, Qian Li, Keguang Chen, Furong Zhao, Haiyan Zhou, Yehui Zhang, John van den Anker, Linlin Song, Wei Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-07-01
Serier:Frontiers in Pharmacology
Fag:
piperacillin/tazobactam
concentration
pediatric
antibacterial effects
target attainment
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2024.1254005/full
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