Granulysin-high decidual NK cells in macaques and humans share signatures of immune defense

Summary: Decidual natural killer cells (dNKs) are key immune effector cells at the maternal-fetal interface. dNKs utilize the antimicrobial peptide granulysin (GNLY) to kill bacteria without killing infected trophoblasts. Since rodents lack the GNLY gene, the in vivo biology of GNLY expression by dN...

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Main Authors: Nina Salinger Prasanphanich, Giulia Protti, Monica Cappelletti, Feiyang Ma, Neema Pithia, Angel Dasenbrock, Jerzy Stanek, Claire A. Chougnet, Suhas G. Kallapur, Matteo Pellegrini, Tamara Tilburgs, Pietro Presicce
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2025-07-01
Series:Cell Reports
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CP: Immunology
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2211124725007144
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