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A Novel Pathway of Functional microRNA Uptake and Mitochondria Delivery

Abstract Extracellular microRNAs (miRNAs) play a critical role in horizontal gene regulation. Uptake of extracellular miRNAs by recipient cells and their intracellular transport, however, remains elusive. Here RNA phase separation is shown as a novel pathway of miRNA uptake. In the presence of serum...

Celý popis

Uloženo v:
Hlavní autoři: Jiachen Liu, Weili Li, Jianfeng Li, Eli Song, Hongwei Liang, Weiwei Rong, Xinli Jiang, Nuo Xu, Wei Wang, Shuang Qu, Shouyong Gu, Yujing Zhang, Chen‐ Yu Zhang, Ke Zen
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2023-08-01
Edice:Advanced Science
Témata:
miRNA uptake
mitochondria
PNPT1
RNA phase separation
On-line přístup:https://doi.org/10.1002/advs.202300452
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