Exercise induces dynamic changes in intra-articular metabolism and inflammation associated with remodeling of the infrapatellar fat pad in mice

Abstract We hypothesized that daily exercise promotes joint health by upregulating anti-inflammatory mediators via adaptive molecular and metabolic changes in the infrapatellar fat pad (IFP). We tested this hypothesis by conducting time-resolved analyses between 1 and 14 days of voluntary wheel runn...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Timothy M. Griffin, Ravi K. Komaravolu, Erika Barboza Prado Lopes, Padmaja Mehta-D’souza, Taylor Conner, Tessa Kovats, Susan Kovats, Madeline Allen, Peyton Harris, Mary Beth Humphrey, Hope D. Welhaven, Priyanka Brahmachary, Ronald K. June
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-01-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Hoffa’s fat pad Adipocyte Synovium Metabolomics Metaflammation Running
Online-Zugang:	https://doi.org/10.1038/s41598-025-86726-0
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