Allicin protects against LPS-induced cardiomyocyte injury by activating Nrf2-HO-1 and inhibiting NLRP3 pathways

Abstract Background Allicin is a bioactive compound with potent antioxidative activity and plays a protective effect in myocardial damage and fibrosis. The role and mechanism of Allicin in septic cardiomyopathy are unclear. In this study, we investigated the effects and underlying mechanisms of Alli...

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Bibliografische Detailangaben

Hauptverfasser:	Fangyuan Sun, Kailiang Xu, Jiayi Zhou, Wei Zhang, Guihe Duan, Ming Lei
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-08-01
Schriftenreihe:	BMC Cardiovascular Disorders
Schlagworte:	Cardiomyocytes Lipopolysaccharide Allicin Apoptosis Inflammation NLR family pyrin domain containing 3
Online-Zugang:	https://doi.org/10.1186/s12872-023-03442-1
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