Generation of a Mouse Model to Study the Noonan Syndrome Gene Lztr1 in the Telencephalon
The leucine zipper-like transcriptional regulator 1 (Lztr1) is a BTB-Kelch domain protein involved in RAS/MAPK pathway regulation. Mutations in LZTR1 are associated with cancers and Noonan syndrome, the most common RASopathy. The expression and function of Lztr1 in the developing brain remains poorl...
שמור ב:
| Principais autores: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Frontiers Media S.A.
2021-06-01
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| סדרה: | Frontiers in Cell and Developmental Biology |
| נושאים: | |
| גישה מקוונת: | https://www.frontiersin.org/articles/10.3389/fcell.2021.673995/full |
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