Deoxycholic acid derived from the gut microbiota involved in the regulation of adaptive thermogenesis in response to dietary protein restriction in plateau pika

Abstract Background Most winter-active mammals experience protein restriction. Gut microbiota is a key regulator of host energy homeostasis during nutrient deficiency, yet cross talk between microbiota and factors (e.g., hormones, signaling molecules) that regulate host energy metabolism in a low-pr...

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Autors principals:	Fuyu Shi, Zhiteng Yang, Liangzhi Zhang, Desheng Zou, Jiangkun Yu, Na Guo, Shien Ren, Xianjiang Tang, Chen Gu, Ruiping Xu, Yuning Ru, Yanming Zhang, Dehua Wang
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2025-12-01
Col·lecció:	Microbiome
Matèries:	Low-protein diet Gut microbiota FGF21 Adaptive thermogenesis Plateau pika (Ochotona curzoniae) Qinghai-Tibetan plateau
Accés en línia:	https://doi.org/10.1186/s40168-025-02233-4
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