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Emerging treatment paradigms with FLT3 inhibitors in acute myeloid leukemia

Mutations in the fms-like tyrosine kinase 3 ( FLT3 ) gene are detected in approximately one-third of patients with newly diagnosed acute myeloid leukemia (AML). These consist of the more common FLT3 -internal tandem duplication (ITD) in approximately 20–25% of AML cases, and point mutations in the t...

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Bibliografiske detaljer
Principais autores: Nicholas J. Short, Hagop Kantarjian, Farhad Ravandi, Naval Daver
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2019-02-01
Serier:Therapeutic Advances in Hematology
Online adgang:https://doi.org/10.1177/2040620719827310
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