Emerging treatment paradigms with FLT3 inhibitors in acute myeloid leukemia
Mutations in the fms-like tyrosine kinase 3 ( FLT3 ) gene are detected in approximately one-third of patients with newly diagnosed acute myeloid leukemia (AML). These consist of the more common FLT3 -internal tandem duplication (ITD) in approximately 20–25% of AML cases, and point mutations in the t...
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| Principais autores: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
SAGE Publishing
2019-02-01
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| Serier: | Therapeutic Advances in Hematology |
| Online adgang: | https://doi.org/10.1177/2040620719827310 |
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