The Effect of Oleanolic Acid and Its Four New Semisynthetic Derivatives on Human MeWo and A375 Melanoma Cell Lines

This study aimed to synthesize four new semisynthetic derivatives of natural oleanolic acid (OA) and, based on an analysis of their cytotoxic and anti-proliferative effects against human MeWo and A375 melanoma cell lines, select those with anti-cancer potential. We also screened the treatment time w...

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Principais autores:	Barbara Bednarczyk-Cwynar, Anna Leśków, Izabela Szczuka, Lucjusz Zaprutko, Dorota Diakowska
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-05-01
Series:	Pharmaceuticals
Assuntos:	triterpenes oleanolic acid derivatives human melanoma cytotoxicity
Acceso en liña:	https://www.mdpi.com/1424-8247/16/5/746
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