Activated notch signaling pathway protects the intestinal barrier in DSS-induced colitis by regulating tight junctions

Abstract Background and aims Studies have suggested that the activation of Notch pathway may provide protection to the intestinal mucosal barrier. However, the underlying mechanism remains to be elucidated. Methods In vivo experiments, the dextran sulfate sodium (DSS)-induced colitis mice were used...

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Detalhes bibliográficos

Principais autores:	Tingting Li, Chong Geng, Xiao Li, Shuailing Song, Yanni Li, Chunhui Wang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	European Journal of Medical Research
Assuntos:	Intestinal mucosal barrier Notch signaling Colitis Tight junction Tumor necrosis factor-α
Acesso em linha:	https://doi.org/10.1186/s40001-026-03941-9
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