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Inhibition of IKK-NFκB pathway sensitizes lung cancer cell lines to radiation

<b>Objective</b> : Cancer cell radioresistance is a stumbling block in radiation therapy. The activity in the nuclear factor kappa B (NFκB) pathway correlates with anti-apoptotic mechanisms and increased radioresistance. The IKK complex plays a major role in NFκB activation upon numerous signals. In...

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Bibliografische Detailangaben
Hauptverfasser: Avgi Tsolou, Maria Liousia, Dimitra Kalamida, Stamatia Pouliliou, Alexandra Giatromanolaki, Michael Koukourakis
Format: Artigo
Sprache:Inglês
Veröffentlicht: China Anti-Cancer Association 2017-06-01
Schriftenreihe:Cancer Biology & Medicine
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Online-Zugang:http://www.cancerbiomed.org/index.php/cocr/article/view/1051
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