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Disc Large Homolog 1 Is Critical for Early T Cell Receptor Micro Cluster Formation and Activation in Human T Cells

T cell activation by antigen involves multiple sequential steps, including T cell receptor-microcluster TCR-(MC) formation, immunological synapse formation, and phosphorylation of mediators downstream of the TCR. The adaptor protein, Disc Large Homolog 1 (DLG1), is known to regulate proximal TCR sig...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: June Guha, Raj Chari
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2021-12-01
Rangatū:Vaccines
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2076-393X/9/12/1446
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