327 Cerebrovascular disease modifies TMEM106B fibril accumulation in neurodegeneration

Objectives/Goals: TMEM106B forms age-dependent amyloid fibrils that are elevated in dementia patients and correlated with increased TDP-43 pathology. Cerebrovascular disease (CVD), a major dementia co-pathology, may contribute to TDP-43 dysfunction. Understanding the relationships among CVD, TMEM106...

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主要な著者:	Matthew Dopler, Cole Corbett, Angelique D. Gonzalez, Ali Ghaseminejad-Bandpey, Mallory Keating, Kyra M. Clarke, Oluwaseun B. Ogunbona, Gladys Maestrae, Sudha Seshadri, Shahroo Etemadmoghadam, Margaret E. Flanagan
フォーマット:	Artigo
言語:	Inglês
出版事項:	Cambridge University Press 2026-04-01
シリーズ:	Journal of Clinical and Translational Science
オンライン･アクセス:	https://www.cambridge.org/core/product/identifier/S2059866126105147/type/journal_article
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