Bisphenol A increases fat mass in adipose tissue by disturbing gut microbiota-dependent bile acid metabolism and TGR5/UCP1 signaling pathways in CD-1 mice

Disorder of gut microbiota-mediated bile acid (BA) metabolism plays a pivotal role in the pathogenesis of obesity. Our previous research showed that bisphenol A (BPA) exposure induced hepatic fat accumulation and gut microbiota dysbiosis. However, whether the gut microbiota-dependent BA metabolism a...

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Автори:	Xiaobing Chen, Jun Zou, Ting Hong, Hongmin Zhang, Jie Yang, Haiyan Mai, Hui Shi, Xin Li, Dan Feng
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2025-09-01
Серія:	Ecotoxicology and Environmental Safety
Предмети:	Bisphenol A Gut microbiota Bile acid Takeda G protein-coupled receptor 5 Uncoupling protein 1 Obesity
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S0147651325012679
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