Therapeutic effects of favipiravir against severe fever with thrombocytopenia syndrome virus infection in a lethal mouse model: Dose-efficacy studies upon oral administration.

Severe fever with thrombocytopenia syndrome (SFTS), caused by SFTS virus (SFTSV), is a viral hemorrhagic fever with a high case fatality rate. Favipiravir was reported to be effective in the treatment of SFTSV infection in vivo in type I interferon receptor knockout (IFNAR-/-) mice at treatment dosa...

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Hlavní autoři:	Hideki Tani, Takashi Komeno, Aiko Fukuma, Shuetsu Fukushi, Satoshi Taniguchi, Masayuki Shimojima, Akihiko Uda, Shigeru Morikawa, Nozomi Nakajima, Yousuke Furuta, Masayuki Saijo
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2018-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC6203377?pdf=render
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