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A role for ceruloplasmin in the control of human glioblastoma cell responses to radiation

Abstract Background Glioblastoma (GB) is the most common and most aggressive malignant brain tumor. In understanding its resistance to conventional treatments, iron metabolism and related pathways may represent a novel avenue. As for many cancer cells, GB cell growth is dependent on iron, which is t...

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Principais autores: Charlotte Roy, Sylvie Avril, Claire Legendre, Bénédicte Lelièvre, Honorine Vellenriter, Sébastien Boni, Jérôme Cayon, Catherine Guillet, Yannick Guilloux, Michel Chérel, François Hindré, Emmanuel Garcion
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-08-01
coleção:BMC Cancer
Assuntos:
Glioblastoma
Radioresistance
Ceruloplasmin
Iron Metabolism
Hypoxia
Acesso em linha:https://doi.org/10.1186/s12885-022-09808-6
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