Identification of hub genes contributing to acute eczema using transcriptome sequencing and machine-learning approaches

Abstract Background Acute eczema (AE) is a multifactorial inflammatory skin disease with complex immune dysregulation. The identification of key pathogenic genes may provide novel biomarkers and therapeutic targets. Methods An AE rat model was induced using DNCB. Transcriptome sequencing was perform...

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Detalhes bibliográficos

Principais autores:	Yingying Zhao, Wenxiu Wang, Xinying Li, Xiaona Ye, Xingjun Han
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2025-12-01
Colecção:	BMC Medical Genomics
Assuntos:	Acute eczema mRNA sequencing Bioinformatics Machine learning ICAM-1
Acesso em linha:	https://doi.org/10.1186/s12920-025-02283-5
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