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CerS1 but Not CerS5 Gene Silencing, Improves Insulin Sensitivity and Glucose Uptake in Skeletal Muscle

Skeletal muscle is perceived as a major tissue in glucose and lipid metabolism. High fat diet (HFD) lead to the accumulation of intramuscular lipids, including: long chain acyl-CoA, diacylglycerols, and ceramides. Ceramides are considered to be one of the most important lipid groups in the generatio...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Agnieszka U. Błachnio-Zabielska, Kamila Roszczyc-Owsiejczuk, Monika Imierska, Karolina Pogodzińska, Paweł Rogalski, Jarosław Daniluk, Piotr Zabielski
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2022-01-01
Schriftenreihe:Cells
Schlagworte:
skeletal muscle
insulin resistance
ceramides
gene silencing
mass spectrometry
Online-Zugang:https://www.mdpi.com/2073-4409/11/2/206
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