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Mechanism of Hsp70 specialized interactions in protein translocation and the unfolded protein response

Hsp70 chaperones interact with substrate proteins in a coordinated fashion that is regulated by nucleotides and enhanced by assisting cochaperones. There are numerous homologues and isoforms of Hsp70 that participate in a wide variety of cellular functions. This diversity can facilitate adaption or...

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Autori principali: Natacha Larburu, Christopher J. Adams, Chao-Sheng Chen, Piotr R. Nowak, Maruf M. U. Ali
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2020-08-01
Serie:Open Biology
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Accesso online:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200089
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