Spatial and temporal heterogeneity in high-grade serous ovarian cancer: a phylogenetic analysis.
<h4>Background</h4>The major clinical challenge in the treatment of high-grade serous ovarian cancer (HGSOC) is the development of progressive resistance to platinum-based chemotherapy. The objective of this study was to determine whether intra-tumour genetic heterogeneity resulting from clonal evol...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science (PLoS)
2015-02-01
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| سلاسل: | PLoS Medicine |
| الوصول للمادة أونلاين: | https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1001789&type=printable |
| الوسوم: |
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