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Hexavalent Chromium (Cr(VI)) Down-Regulates Acetylation of Histone H4 at Lysine 16 through Induction of Stressor Protein Nupr1.

The environmental and occupational carcinogen Hexavalent Chromium (Cr(VI)) has been shown to cause lung cancer in humans when inhaled. In spite of a considerable research effort, the mechanisms of Cr(VI)-induced carcinogenesis remain largely unknown. Nupr1 (nuclear protein 1) is a small, highly basi...

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Bibliografski detalji
Glavni autori: Danqi Chen, Thomas Kluz, Lei Fang, Xiaoru Zhang, Hong Sun, Chunyuan Jin, Max Costa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2016-01-01
Serija:PLoS ONE
Online pristup:https://doi.org/10.1371/journal.pone.0157317
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