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In Silico Design and Characterization of the Essential Outer-Membrane Lipoprotein LolB-Derived Multi-Epitope Vaccine Candidate Against <i>Pseudomonas aeruginosa</i>

<i>Pseudomonas aeruginosa</i> causes severe healthcare-associated infections, yet no vaccine has been licenced. To circumvent the antigenic variability of classical surface antigens, we evaluated LolB—an essential outer-membrane lipoprotein whose periplasmic orientation favours T-cell-dominant mecha...

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Hlavní autoři: Sinethemba H. Yakobi, Uchechukwu U. Nwodo
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2026-04-01
Edice:Methods and Protocols
Témata:
<i>Pseudomonas aeruginosa</i>
LolB
multi-epitope vaccine
molecular dynamics
TLR4/MD-2
immunoinformatics
On-line přístup:https://www.mdpi.com/2409-9279/9/2/52
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