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Doxycycline PEP can induce doxycycline resistance in Klebsiella pneumoniae in a Galleria mellonella model of PEP

BackgroundFour randomized controlled trials have now established that doxycycline post exposure (sex) prophylaxis (PEP) can reduce the incidence of chlamydia and syphilis in men who have sex with men. These studies have concluded that the risk of selecting for antimicrobial resistance is low. We eva...

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Huvudupphov: Chris Kenyon, Zina Gestels, Thibaut Vanbaelen, Said Abdellati, Dorien Van Den Bossche, Irith De Baetselier, Basil Britto Xavier, Sheeba Santhini Manoharan-Basil
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2023-08-01
Serie:Frontiers in Microbiology
Ämnen:
Neisseria gonorrhoeae
Klebsiella pneumoniae
doxycycline PEP
WGS
in-vivo emergence
DoxyPEP
Länkar:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1208014/full
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