The interleukin-4/PPARγ signaling axis promotes oligodendrocyte differentiation and remyelination after brain injury.

The repair of white matter damage is of paramount importance for functional recovery after brain injuries. Here, we report that interleukin-4 (IL-4) promotes oligodendrocyte regeneration and remyelination. IL-4 receptor expression was detected in a variety of glial cells after ischemic brain injury,...

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Hlavní autoři:	Qingxiu Zhang, Wen Zhu, Fei Xu, Xuejiao Dai, Ligen Shi, Wei Cai, Hongfeng Mu, T Kevin Hitchens, Lesley M Foley, Xiangrong Liu, Fang Yu, Jie Chen, Yejie Shi, Rehana K Leak, Yanqin Gao, Jun Chen, Xiaoming Hu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2019-06-01
Edice:	PLoS Biology
On-line přístup:	https://doi.org/10.1371/journal.pbio.3000330
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