Endoxifen-glucuronide and 4-hydroxy-tamoxifen glucuronide are substrates of OATP1A2
Tamoxifen is a widely prescribed antiestrogen for breast cancer therapy that undergoes P450-mediated formation of the active metabolites 4-hydroxy-tamoxifen (4-OH-tamoxifen) and endoxifen prior to glucuronidation. Organic anion-transporting polypeptides (OATPs) OATP1A2 and OATP2B1 are known to be ex...
I tiakina i:
| Ngā kaituhi matua: | , , , |
|---|---|
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Elsevier
2026-01-01
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| Rangatū: | ASPET Discovery |
| Ngā marau: | |
| Urunga tuihono: | http://www.sciencedirect.com/science/article/pii/S3050567426000039 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
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