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TCR-L: an analysis tool for evaluating the association between the T-cell receptor repertoire and clinical phenotypes

Abstract Background T cell receptors (TCRs) play critical roles in adaptive immune responses, and recent advances in genome technology have made it possible to examine the T cell receptor (TCR) repertoire at the individual sequence level. The analysis of the TCR repertoire with respect to clinical p...

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Hoofdauteurs: Meiling Liu, Juna Goo, Yang Liu, Wei Sun, Michael C. Wu, Li Hsu, Qianchuan He
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2022-04-01
Reeks:BMC Bioinformatics
Onderwerpen:
Association test
CDR3
Clinical phenotypes
T cell receptors
TCR homology
TCR repertoire
Online toegang:https://doi.org/10.1186/s12859-022-04690-2
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