High-dose vitamin C promotes mitochondrial biogenesis in HCT116 colorectal cancer cells by regulating the AMPK/PGC-1α signaling pathway

Abstract Background Mitochondrial dysfunction is closely associated with cancer development. Colorectal cancer (CRC) cells often exhibit altered energy metabolism, characterized by increased glycolysis and reduced oxidative phosphorylation. Enhancing mitochondrial biogenesis and function may represe...

Celý popis

Podrobná bibliografie

Hlavní autoři:	RuiYang Hong, Su Min, Jia Huang, Mou Zou, DongYu Zhou, Yun Liang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2025-05-01
Edice:	Journal of Cancer Research and Clinical Oncology
Témata:	Vitamin C Colorectal cancer Mitochondrial biogenesis AMPK PGC-1α
On-line přístup:	https://doi.org/10.1007/s00432-025-06211-z
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!