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Hypoxia drives spermatogenic impairment by triggering lysosome-dependent death of Leydig cells via M1 macrophage polarization

Abstract Objective To investigate the critical role of hypoxia in impairing spermatogenesis via M1 macrophage polarization and subsequent induction of lysosome-dependent cell death (LDCD) in Leydig cells. Methods Ten eight-week-old male SD rats (weight 220~250 g) were randomly divided into normo...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: MENG Dan, HE Wei, ZENG Jitao
Format: Artigo
Sprache:Chinês
Veröffentlicht: Editorial Office of Journal of Army Medical University 2025-12-01
Schriftenreihe:陆军军医大学学报
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Online-Zugang:https://aammt.tmmu.edu.cn/html/202510077.html
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