Coffee extract inhibits adipogenesis in 3T3-L1 preadipocyes by interrupting insulin signaling through the downregulation of IRS1.

Although epidemiological data have indicated that a strong negative association exists between coffee consumption and the prevalence of obesity-associated diseases, the molecular mechanisms by which coffee intake prevents obesity-associated diseases has not yet been elucidated. In this study, we fou...

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Hlavní autoři:	Chihiro Maki, Megumi Funakoshi-Tago, Ryohei Aoyagi, Fumihito Ueda, Masaki Kimura, Kenji Kobata, Kenji Tago, Hiroomi Tamura
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2017-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC5345824?pdf=render
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