Loss of monoacylglycerol O-acyltransferase 2 can be compensated for by diacylglycerol O-acyltransferases 1 and 2 resulting in a negligible influence on mammary cancer development found in a mouse model and verified in human tissues

Background: Dietary fat absorption involves the re-esterification of digested triacylglycerol in the enterocytes, it is a biological process catalyzed by monoacylglycerol O-acyltransferase 2 (MOGAT2, aka MGAT2), which is highly expressed in the small intestine. A previous study showed that the loss...

Whakaahuatanga katoa

Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Mei Yan, Wang Jing, Lu Jia-Bin, Lu Guan-Ming, Peng Li-Xia, Lang Yan-Hong, Zheng Li-Sheng, Huang Bi-Jun, Shi Yan-Xia, Qian Chao-Nan
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	EDP Sciences 2023-01-01
Rangatū:	Visualized Cancer Medicine
Ngā marau:	mogat2 depletion mmtv-pymt mammary tumor dgat1 dgat2
Urunga tuihono:	https://vcm.edpsciences.org/articles/vcm/full_html/2023/01/vcm20230004/vcm20230004.html
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!