Steroidal antibiotics are antimetabolites of Acanthamoeba steroidogenesis with phylogenetic implications
Pathogenic organisms may be sensitive to inhibitors of sterol biosynthesis, which carry antimetabolite properties, through manipulation of the key enzyme, sterol methyltransferase (SMT). Here, we isolated natural suicide substrates of the ergosterol biosynthesis pathway, cholesta-5,7,22,24-tetraenol...
Guardat en:
| Autors principals: | , , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2019-05-01
|
| Col·lecció: | Journal of Lipid Research |
| Matèries: | |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S0022227520322689 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|