An immuno-lipidomic signature revealed by metabolomic and machine-learning approaches in labial salivary gland to diagnose primary Sjögren’s syndrome

IntroductionAssessing labial salivary gland exocrinopathy is a cornerstone in primary Sjögren’s syndrome. Currently this relies on the histopathologic diagnosis of focal lymphocytic sialadenitis and computing a focus score by counting lym=phocyte foci. However, those lesions represent advanced stage...

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Detalhes bibliográficos

Principais autores:	Geoffrey Urbanski, Floris Chabrun, Estelle Delattre, Carole Lacout, Brittany Davidson, Odile Blanchet, Juan Manuel Chao de la Barca, Gilles Simard, Christian Lavigne, Pascal Reynier
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-07-01
coleção:	Frontiers in Immunology
Assuntos:	kynurenine biomarker metabolomics Sjögren’s syndrome sicca salivary glands
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1205616/full
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