Identification of a novel β-1,4-galactosyltransferase from Haemophilus parainfluenzae for efficient biosynthesis of lacto-N-neotetraose in Escherichia coli

As an important member of human milk oligosaccharides (HMOs), lacto-N-neotetraose (LNnT) has been recognized as a promising HMO with many physiological activities for infants. β-1,4-Galactosyltransferases play a vital role in the final step of LNnT biosynthesis in microbial cell factory. Herein, we...

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Principais autores:	Dan Liu, Chenhui Ying, Yingqi Ping, Shanquan Liang, Qiaojuan Yan, Zhengqiang Jiang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	KeAi Communications Co., Ltd. 2026-03-01
coleção:	Synthetic and Systems Biotechnology
Assuntos:	Escherichia coli Human milk oligosaccharides Lacto-N-neotetraose β-1,4-Galactosyltransferase Biosynthesis
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405805X25001474
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