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Electroacupuncture prevents CUMS induced depressive-like behaviors by inhibiting microglia-mediated synaptic pruning induced by gut dysbiosis

Abstract Rationale Electroacupuncture (EA) has been widely used for depression treatment. Microbiota-gut-brain (MGB) axis plays a vital role in regulating emotional behaviors. However, the potential role of MGB axis in EA-mediated protective effects remains unclear. Methods The protective effects of...

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Gardado en:
Principais autores: Lu Zhang, Jingyi Quan, Linlin Nie, Shenglan He, Yeze Lin, Xiaoxiao Liu, Yifan Zhang, Lixing Zhuang, Chao Jia, Min Li, Qi Wang, Lining Duan
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2026-05-01
Series:Chinese Medicine
Assuntos:
Electroacupuncture
Depression
Microglia
Synaptic pruning
Gut dysbiosis
Acceso en liña:https://doi.org/10.1186/s13020-026-01422-z
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