Development of a Mouse Model of Hematopoietic Loss of Y Chromosome
This protocol describes the generation of chimeric mice in which the Y chromosome is deleted from a proportion of blood cells. This model recapitulates the phenomenon of hematopoietic mosaic loss of Y chromosome (mLOY), which is frequently observed in the blood of aged men. To construct mice with he...
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| Principais autores: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bio-protocol LLC
2023-08-01
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| coleção: | Bio-Protocol |
| Acesso em linha: | https://bio-protocol.org/en/bpdetail?id=4729&type=0 |
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