Profiling of circulating T-cells with prognostic and predictive value in early and advanced stage PDAC

Abstract Pancreatic Ductal Adenocarcinoma (PDAC) is a lethal malignancy with few treatment options. Despite the promising results of immunotherapy in various solid cancers, the efficacy of immunotherapy in PDAC is poor. Therefore, deciphering immune responses is pivotal for the development of novel...

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Autori principali:	Anastasia Xagara, Konstantina Vasilieva, Alexandros Kokkalis, Alexandros Lazarou, George Christodoulopoulos, Vasileios Papadopoulos, Evangelia Chantzara, Fillipos Koinis, Emmanouil Saloustros, Galatea Kallergi, Vassilis Georgoulias, Ioannis S. Pateras, Athanasios Kotsakis
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Springer 2025-10-01
Serie:	Cancer Immunology, Immunotherapy
Soggetti:	PDAC T-cell exhaustion TCF1 PD-1
Accesso online:	https://doi.org/10.1007/s00262-025-04190-1
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