Tumor Mutation Burden Predicts Relapse in Papillary Thyroid Carcinoma With Changes in Genes and Immune Microenvironment

BackgroundThe risk factors of papillary thyroid carcinoma (PTC) recurrence are meaningful for patients and clinicians. Tumor mutation burden (TMB) has been a biomarker for the effectiveness of immune checkpoint inhibitor (ICI) and prognosis in cancer. However, the role of TMB and its latent signific...

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Detalhes bibliográficos

Principais autores:	Mengli Guo, Zhen Chen, Yayi Li, Sijin Li, Fei Shen, Xiaoxiong Gan, Jianhua Feng, Wensong Cai, Qingzhi Liu, Bo Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-06-01
Colecção:	Frontiers in Endocrinology
Assuntos:	papillary thyroid carcinoma (PTC) prognosis The Cancer Genome Atlas (TCGA) tumor mutation burden (TMB) immune infiltrate
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fendo.2021.674616/full
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