Polycystin‐1 Mutant Alters Mechanotransduction in Response to Collagen and Extracellular Matrix Stiffness via Daam1‐Dependent Microfilament Remodeling

Abstract Extracellular matrix (ECM) stiffness‐mediated mechanotransduction is a common signaling scheme in both physiological and pathological contexts; however, its molecular mechanisms remain incompletely understood. Polycystin‐1 is a transmembrane protein that is known to participate in mechano‐t...

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Auteurs principaux:	Jiaofeng Zhou, Yibing Deng, Jie Mei, Mengyun Wan, Ningyi Xue, Xinyu Zong, Ji Zhou, Junli Ding, Ting Yan, Yu Jiang, Tiansong Xia, Peng Zheng, Yichao Zhu
Format:	Artigo
Langue:	Inglês
Publié:	Wiley 2025-11-01
Collection:	Advanced Science
Sujets:	Daam1 extracellular matrix mechanotransduction microfilament polycystin‐1
Accès en ligne:	https://doi.org/10.1002/advs.202509846
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