Synthesis, pharmacokinetic studies, and metabolite analysis of meridianin C in rats using a validated ultra high performance liquid chromatography-tandem mass spectrometry method
IntroductionMeridianin C (MC) is a marine-derived indole alkaloid that has demonstrated kinase inhibitory and anti-tumor activities. Despite its diverse biological properties, no previous reports have systematically evaluated the in vivo quantitative analysis of MC and its metabolites.MethodsIn this...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Frontiers Media S.A.
2025-09-01
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| coleção: | Frontiers in Pharmacology |
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| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1633157/full |
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