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Deletion of N-acetylmuramyl-L-alanine amidases alters the host immune response to Mycobacterium tuberculosis infection

Peptidoglycan (PG), a heteropolysaccharide component of the mycobacterial cell wall can be shed during tuberculosis infection with immunomodulatory consequences. As such, changes in PG structure are expected to have important implications on disease progression and host responses during infection wi...

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Principais autores: Nathan Scott Kieswetter, Mumin Ozturk, Shelby-Sara Jones, Sibusiso Senzani, Melissa Dalcina Chengalroyen, Frank Brombacher, Bavesh Kana, Reto Guler
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2021-12-01
coleção:Virulence
Assuntos:
mycobacterium tuberculosis
amidase
ami1
ami4
immunopathology
mice
macrophage
host–pathogen interaction
mutant
Acesso em linha:http://dx.doi.org/10.1080/21505594.2021.1914448
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