Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae.
Translation of mRNA into a polypeptide is terminated when the release factor eRF1 recognizes a UAA, UAG, or UGA stop codon in the ribosomal A site and stimulates nascent peptide release. However, stop codon readthrough can occur when a near-cognate tRNA outcompetes eRF1 in decoding the stop codon, r...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2021-04-01
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| Col·lecció: | PLoS Genetics |
| Accés en línia: | https://doi.org/10.1371/journal.pgen.1009538 |
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