Histone H3 core domain in chromatin with different DNA linker lengths studied by 1H-Detected solid-state NMR spectroscopy

Chromatin, a dynamic protein-DNA complex that regulates eukaryotic genome accessibility and essential functions, is composed of nucleosomes connected by linker DNA with each nucleosome consisting of DNA wrapped around an octamer of histones H2A, H2B, H3 and H4. Magic angle spinning solid-state nucle...

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Hauptverfasser:	Sean T. Smrt, Nicole Gonzalez Salguero, Justin K. Thomas, Mohamad Zandian, Michael G. Poirier, Christopher P. Jaroniec
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2023-01-01
Schriftenreihe:	Frontiers in Molecular Biosciences
Schlagworte:	chromatin nucleosome array histone linker DNA magic angle spinning (MAS) solid-state NMR
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmolb.2022.1106588/full
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