Development and Characterization of a cDNA-Launch Recombinant Simian Hemorrhagic Fever Virus Expressing Enhanced Green Fluorescent Protein: ORF 2b’ Is Not Required for In Vitro Virus Replication

Simian hemorrhagic fever virus (SHFV) causes acute, lethal disease in macaques. We developed a single-plasmid cDNA-launch infectious clone of SHFV (rSHFV) and modified the clone to rescue an enhanced green fluorescent protein-expressing rSHFV-eGFP that can be used for rapid and quantitative detectio...

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Detalhes bibliográficos

Principais autores:	Yingyun Cai, Shuiqing Yu, Ying Fang, Laura Bollinger, Yanhua Li, Michael Lauck, Elena N. Postnikova, Steven Mazur, Reed F. Johnson, Courtney L. Finch, Sheli R. Radoshitzky, Gustavo Palacios, Thomas C. Friedrich, Tony L. Goldberg, David H. O’Connor, Peter B. Jahrling, Jens H. Kuhn
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2021-04-01
coleção:	Viruses
Assuntos:	<i>Arteriviridae</i> cell tropism infectious clone <i>Nidovirales</i> reverse genetics SHFV
Acesso em linha:	https://www.mdpi.com/1999-4915/13/4/632
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