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Extracellular Onchocerca-derived small RNAs in host nodules and blood

Abstract Background microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by parasitic nematodes in exosomes and have been detected in the serum of murine and dog hosts infected with the filarial ne...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Juan F Quintana, Benjamin L Makepeace, Simon A Babayan, Alasdair Ivens, Kenneth M Pfarr, Mark Blaxter, Alexander Debrah, Samuel Wanji, Henrietta F Ngangyung, Germanus S Bah, Vincent N Tanya, David W Taylor, Achim Hoerauf, Amy H Buck
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2015-01-01
Schriftenreihe:Parasites & Vectors
Schlagworte:
microRNAs
Extracellular RNA
Filarial nematode
Onchocerciasis
Host-pathogen
Online-Zugang:https://doi.org/10.1186/s13071-015-0656-1
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