MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers.

MicroRNAs are key regulators of gene expression and have been shown to have altered expression in a variety of cancer types, including epithelial ovarian cancer. MiRNA function is most often achieved through binding to the 3'-untranslated region of the target protein coding gene. Mutation screening...

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Автори:	Georgina L Ryland, Jennifer L Bearfoot, Maria A Doyle, Samantha E Boyle, David Y H Choong, Simone M Rowley, Australian Ovarian Cancer Study Group, Richard W Tothill, Kylie L Gorringe, Ian G Campbell
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Public Library of Science (PLoS) 2012-01-01
Серія:	PLoS ONE
Онлайн доступ:	https://doi.org/10.1371/journal.pone.0035805
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MicroRNA genes and their target 3'-untranslated regions are infrequently somatically mutated in ovarian cancers.

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